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The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the advantages of the drug outweighs the chance of a possible rise in blood pressure. Using two separate drugs to shed weight can be very effective you'll find combinations while watching FDA now awaiting approval. When dealing with fat loss and the those who go through it you should err assisting caution and allow FDA do its job and demand some investigation be done in order that the public understands the side effects and hazards of the medications before we drive them. Keep in mind that drug companies have been in business to generate money and that they would say everything to keep people on his or her medications. Researchers found that participants taking this drug to get a year, dropped excess weight within a month and have kept the extra weight off during the entire 56 weeks from the study. Contrave is a combination in the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which might be made up of multiple active ingredient, which might make them more efficient and safer. Combo-pilling is the newest fad or better yet the newest in the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is becoming popular could be the fact that as of right now there aren't long term prescription weight loss supplements that have been licensed by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures certainly are a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug also can raise blood pressure and heart rate, and really should not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug. The FDA also warned that Contrave can raise hypertension and pulse rate and must stop used in patients with uncontrolled high blood pressure level, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients for the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for stop smoking. Acamprosate also works to eliminate the wish to drink through the elimination of the the cravings for alcohol consumption. The major difference between Naltrexone and Acamprosate is the fact that Acamprosate isn't yet for sale in the United States. While it continues to be widely studied in Europe the exact chemical belief that it works remains unknown. It is believed that it disrupts receptors in the brain which process glutamate, which in essence alters the way ones body reacts to alcohol intake. Several of the European research has shown a lot of promise with Acamprosate because some of the patients had a practically double rate of success for staying sober.